VM migration (vMotion) from some other environments (rack servers, other blades chassis) to HPE Synergy can cause lost of the connectivity.
The main problem is that it is not happening every time. It is like 5-10% all migrations has problems rest of them runs smoothly.
The main reason may be firmware version of VC modules in Synergy.
In this situation stale entry of MAC address may be left on one of the VC modules. In theory restart of one of the VC could help (and usually this helped). It is also the simplest way to check if you are hitting this issues.
If you are running VC with firmware version 1.5.0.1004 or 2.0.0-1006 you have to upgrade to at least version 1.6.0 or 2.1.0.1003.
More details here: https://support.hpe.com/hpesc/public/docDisplay?docId=emr_na-a00099081en_us
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